Sasaki T, Shiohama A, Kubo A, Kawasaki H, Ishida-Yamamoto A, Yamada T, Hachiya T, Shimizu A, Okano H, Kudoh J, Amagai M.: ![]() "Dysbiosis and Staphylococcus aureus colonization drives inflammation in atopic dermatitis." Kobayashi T, Glatz M, Horiuchi K, Kawasaki H, Akiyama H, Kaplan DH, Kong HH, Amagai M, Nagao K.: "Epidermal cell turnover across tight junctions based on Kelvin's tetrakaidecahedron cell shape." Yokouchi M, Atsugi T, Logtestijn MV, Tanaka RJ, Kajimura M, Suematsu M, Furuse M, Amagai M, Kubo A.: Inflammation-free, gas-permeable, lightweight, stretchable on-skin electronics with nanomeshes. Miyamoto A, Lee S, Cooray NF, Lee S, Mori M, Matsuhisa N, Jin H, Yoda L, Yokota T, Itoh A, Sekino M, Kawasaki H, Ebihara T, Amagai M, Someya T.: "Holocrine Secretion Occurs outside the Tight Junction Barrier in Multicellular Glands: Lessons from Claudin-1-Deficient Mice." "Filaggrin expression and processing deficiencies impair corneocyte surface texture and stiffness in mice."Ītsugi T, Yokouchi M, Hirano T, Hirabayashi A, Nagai T, Ohyama M, Abe T, Kaneko M, Zouboulis CC, Amagai M, Kubo A.: ![]() Thyssen JP, Jakasa I, Riethmüller C, Schön MP, Braun A, Haftek M, Fallon PG, Wróblewski J, Jakubowski H, Eckhart L, Declercq W, Koppes S, Engebretsen KA, Bonefeld C, Irvine AD, Keita-Alassane S, Simon M, Kawasaki H, Kubo A, Amagai M, Matsui T, Kezic S.: "A unique mode of keratinocyte death requires intracellular acidification." Matsui T, Kadono-Maekubo N, Suzuki Y, Furuichi Y, Shiraga K, Sasaki H, Ishida A, Sonoko Takahashi S, Okada T, Toyooka K, Sharif J, Abe T, Kiyonari H, Tominaga M, Miyawaki A, Amagai M.: "Staphylococcus cohnii is a potentially biotherapeutic skin commensal alleviating skin inflammation." Ito Y, Sasaki T, Li Y, Tanoue T, Sugiura Y, Skelly AN, Suda W, Kawashima Y, Okahashi N, Watanabe E, Horikawa H, Shiohama A, Kurokawa R, Kawakami E, Iseki H, Kawasaki H, Iwakura Y, Shiota A, Yu L, Hisatsune J, Koseki H, Sugai M, Arita M, Ohara O, Matsui T, Suematsu M, Hattori M, Atarashi K, Amagai M, Honda K.: Papers with an asterisk(*) are based on research conducted outside of RIKEN. Our research group is trying to reveal the entire picture of the skin as an immune organ, clarify the pathophysiological mechanisms of allergic and autoimmune diseases, and develop novel therapeutic strategies based on their molecular mechanisms. Skin is the place where sensitization to external antigens as well as peripheral tolerance to autoantigen take place. Many of these skin diseases are caused by immunological abnormalities. Skin diseases have been categorized based on the morphology of skin lesions, which are now being explained with molecular mechanisms. turns universal indicator solution blue or purpleĬomplete the word equation and balanced symbol equation for the reaction of potassium with water.Skin is an organ which covers the outer surface of living bodies. ![]() It is a base that dissolves in water to form an alkaline solution. Sodium + water → sodium hydroxide + hydrogen The alkali metals react with water to produce a metal hydroxide and hydrogen. The ions have a stable arrangement of electrons, with a complete outer shell. When a group 1 element takes part in a reaction, its atoms each lose one electron. This means that the alkali metals all have similar chemical properties. Chemical properties of group 1 elementsĪtoms of group 1 elements all have one electron in their outer shell. Going down group 1, the melting point decreases.
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